A few years back, Rebecca Helm, a biologist then working as an assistant professor at the University of North Carolina, wrote an X post encapsulating all we know these days about sex and gender. That is, what people who study human S&G, professionally and seriously, know about the stuff.
Scads of folks out there feel certain to their cores that they know all about it, but they don’t. What they know is a bunch of fuzzy chatter passed down through the generations, based on preconceptions, misconceptions, and outright bullshit, none of which helps them or us understand the true nature of our sexuality and gender self-identity.
Most people believe any and every human being is one or the other, female or male. That’s it. No argument tolerated. No uncertainty allowed.
If only it were that simple
Then again saying “if only…” implies things’d be better that way. Easier to understand, maybe. But better? No.
There are more than a few critters in this world who are both male and female. They include earthworms, moss animals (bryozoans), flukes (trematodes), snails, banana slugs, clownfish, certain types of wrasse fish, mangrove rivulus fish, and barnacles.
I suppose the social media pages shared by the Earth’s barnacles are not rife with uninformed pontifications on which one is a boy or girl since they all are both. See? Easy.
Recall how “gender reveal” parties were big among expecting parents a few years back? The future moms and dads’d send out invitations to all their friends and relatives saying, Wahoo, we’re gonna have a young’n! Let’s get sloshed and pig out on seven-bean salad. Everybody would come by and the parents would reveal the results of their fetal anatomy tests so that all the attendees would then know what color onesies to buy for the upcoming baby showers.
That fad seems to be either dying off or becoming something to be shunned, rather like those antebellum plantation dress up parties that were all the rage for a while. Here’s a thread from a website called what to expect, an all-around discussion forum and registry for expectant parents: “Gender Reveal Parties… Are They Even Still a Thing?” Comments range from “They are so FUN! Cupcakes or cake w fam and friends will never go out of style!” to “Gender reveal parties don’t reveal the gender of the baby, but the sex of the baby, AKA what their private parts look like.”
Even that latter comment, albeit semi-enlightened, reeks of old school twaddle. Private parts? Really?
Anyway, a certain swath of the populace now embraces the notion that gender and sex aren’t the same things and that the binary nature of the terms fails to accurately represent the reality of things. Those folks are labeled “woke” (in the pejorative sense) by another swath that says a boy’s a boy and a girl’s a girl and if you believe otherwise you must be a commie rat.
So, here comes the aforementioned biologist Rebecca Helm with her straightforward, indispensable take on what we oughtta know (her prose is cleaned and brushed here inasmuch as she’s a hard science nerd, not an English grammar and usage maven):
Lots of folks make biological sex seem really simple. Well, since it’s so simple, let’s find the biological roots, shall we? Let’s talk about sex.
If you know a bit about biology you will probably say that biological sex is caused by chromosomes: XX and you’re female, XY and you’re male. This is “chromosomal sex” but is it “biological sex”?

Human Chromosomes.
Well, turns out there is only one gene on the Y chromosome that really matters to sex. It’s called the SRY gene. During human embryonic development the SRY protein turns on male-associated genes. Having an SRY gene makes you “genetically male.”
But is this “biological sex”?
Sometimes that SRY gene pops off the Y chromosome and over to an X chromosome. Surprise! So now you’ve got an X with an SRY and a Y without an SRY. What does this mean?
A Y with no SRY means physically you’re female, chromosomally you’re male (XY) and genetically you’re female (no SRY). An X with an SRY means you’re physically male, chromsomally female (XX) and genetically male (SRY).
But biological sex is simple! There must be another answer.
Sex-related genes ultimately turn on hormones in specific areas on the body as well as reception of those hormones by cells throughout the body. Is this the root of “biological sex”?
Hormonal male means you produce “normal” levels of male-associated hormones. Except some percentage of females will have higher levels of “male” hormones than some percentage of males. Ditto “female” hormones. And if you’re developing, your body may not produce enough hormones for your genetic sex. Leading you to be genetically male or female, chromosomally male or female, hormonally non-binary, and physically non-binary.
Well, except cells have something to say about this. Maybe cells are the answer to biological sex? Right?
Cells have receptors that “hear” the signal from sex hormones. But sometimes those receptors don’t work. Like a mobile phone that’s on Do Not Disturb.
What does this all mean?
It means you may be genetically male or female, chromosomally male or female, hormonally male/female/non-binary, with cells that may or may not hear the male/female/non-binary call, and all this leading to a body that can be male/non-binary/female.
Try out some combinations for yourself. Notice how confusing it gets? Can you point to what the absolute cause of biological sex is? Is it fair to judge people by it?
Of course you could try appealing to the numbers. “Most people are either male or female,” you say. Except that as a biologist professor I will tell you the reason I don’t have my students look at their own chromosomes in class is because people could learn that their chromosomal sex doesn’t match their physical sex, and learning that in the middle of a 10-point assignment is just not the time.
Biological sex is complicated. Before you discriminate against someone on the basis of biological sex and identity, ask yourself: Have you seen your chromosomes? Do you know the genes of the people you love? The hormones of the people you work with? The state of their cells?
Since the answer will obviously be no, please be kind, respect people’s right to tell you who they are, and remember that you don’t have all the answers. Again, biology is complicated. Kindness and respect don’t have to be.
Note: Biological classifications exist: XX, XY, XXY XXYY, and all manner of variation which is why sex isn’t classified as binary. You can’t have a binary classification system with more than two configurations even if two of those configurations are more common than others.
Biology is a shitshow. Be kind to people.
I guess my buying into Professor Helm’s argument makes me a commie rat. Or just “woke.”
